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NAD+ Drips and Peptides: Could Biohacking Change Anti-Ageing?

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Anti-ageing has traditionally focused on the skin, with sunscreen, retinoids, injectables, lasers and other cosmetic treatments used to address visible signs of ageing. Now, the conversation is moving towards treatments that claim to influence ageing from inside the body.

NAD+ drips and peptide therapies have become part of the growing longevity and biohacking market, with clinics promoting them for energy, recovery, metabolism and healthy ageing. Celebrity and influencer interest has also brought these treatments to a wider audience.

The science, however, is more complicated than the marketing.

Why NAD+ Is Getting Attention

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Nicotinamide adenine dinucleotide, or NAD+, is a coenzyme found throughout the body. It plays a role in energy production, cellular signalling and DNA repair. NAD+ availability appears to change with age, prompting researchers to investigate whether increasing it could influence some processes associated with ageing.

One of the more visible treatments is intravenous NAD+, delivered through a drip. Wellness clinics promote NAD+ infusions for concerns including fatigue, recovery, cognitive function and longevity.

But understanding what NAD+ does biologically is different from proving that an infusion slows ageing.

A 2026 systematic review in Ageing Research Reviews found evidence that oral NAD+ precursors, including nicotinamide riboside and nicotinamide mononucleotide, can increase NAD-related biomarkers. However, evidence that these changes consistently translate into meaningful improvements in health remains limited.

The distinction is important because changing a biological marker does not automatically mean fewer wrinkles, better memory, improved physical performance or a longer lifespan.

There is also a difference between oral NAD+ precursors and intravenous NAD+. A 2026 study of commercially administered IV NAD+ reported short-term findings, including tolerability and exploratory metabolic outcomes, but this does not establish that NAD+ infusions slow human ageing.

Where Peptides Fit In

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Peptides are short chains of amino acids that perform different functions in the body. Some peptide-based medicines have established medical uses, while others are still being investigated.

At the same time, peptides are increasingly marketed through longevity clinics and online communities for claims involving muscle recovery, fat loss, sleep, skin health and other aspects of ageing.

This makes the word “peptide” particularly easy to misunderstand. An approved peptide medicine and an experimental compound marketed online for longevity do not have the same evidence, regulation or safety profile.

Peptides are also common in topical skincare, where certain formulations are marketed to improve the appearance of firmness and fine lines. Applying a peptide serum to the skin, however, is very different from injecting a peptide into the body. The route of administration affects the dose, potential risks and biological effects.

What Does Biohacking Really Offer?

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Longevity research is investigating processes including cellular energy production, DNA repair, inflammation, mitochondrial function and metabolic health. NAD+ is part of this research because of its role in several cellular processes.

But promising biological research does not automatically produce a proven treatment.

For consumers considering a longevity therapy, the important questions are what has actually been tested, in whom, at what dose, by which route and for what outcome.

Cost is another consideration. Repeated infusions or injectable treatments can become expensive, particularly when they are offered as ongoing wellness programmes.

There are also safety questions. IV treatment is an invasive procedure, while injectable peptides may carry risks related to the compound, dosing, contamination or product quality. These concerns are particularly relevant when substances are obtained through poorly regulated online sources.

Conclusion

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Some of the best-supported approaches to healthy ageing remain conventional: regular exercise, adequate sleep, a balanced diet, avoiding smoking and managing cardiovascular risk.

That does not mean NAD+ or peptide research should be dismissed. Some treatments may eventually prove useful for specific aspects of ageing or age-related disease.

For now, though, the evidence does not support treating NAD+ drips or experimental peptide injections as established anti-ageing therapies.

The next step is better human research showing whether changing these biological pathways produces meaningful improvements in health and function over time. Until then, biohacking remains an emerging area of longevity research, not a proven shortcut to slowing ageing.

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Beauty

How to Use Honey to Soothe Dry, Chapped Lips

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Dry, chapped lips can become uncomfortable quickly, particularly when the skin starts to peel or crack. While a good lip balm is usually the simplest option, honey is another ingredient sometimes used to soothe dry lips.

Honey has humectant properties, which means it can help draw and retain moisture. It also has antimicrobial and anti-inflammatory properties that have been studied in wound care. These properties are part of the reason honey appears in skincare remedies, although evidence specifically supporting ordinary household honey as a treatment for chapped lips is limited.

How to apply honey to chapped lips

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If you want to try honey, start with clean lips. Rinse gently with lukewarm water and pat them dry. Avoid scrubbing or removing peeling skin, as this can cause further irritation.

Apply a small amount of plain, food-grade honey to your lips using a clean fingertip. Some beauty guides recommend leaving it on for a few minutes before gently rinsing it off with lukewarm water.

There is no need to apply a thick layer. If your lips are very dry, follow with a plain, fragrance-free lip ointment to help reduce moisture loss.

Honey is not a replacement for lip ointment

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Honey may provide temporary soothing, but it should not replace basic lip care. Dermatologists commonly recommend bland, non-irritating products containing ingredients such as petrolatum, mineral oil, ceramides, dimethicone or shea butter for dry, chapped lips.

Petrolatum, in particular, forms a protective layer that helps prevent water from escaping from the skin. This can be especially useful when lips are cracked or repeatedly becoming dry.

During the day, remember to protect your lips from the sun. Choose a lip product with SPF 30 or higher when spending time outdoors, as sun exposure can contribute to dry and damaged lips.

Avoid habits that prolong chapping

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Lip licking can make dryness worse. Saliva evaporates quickly, and repeatedly wetting the lips can contribute to further irritation. Picking or biting peeling skin can also delay healing.

It is also worth checking the ingredients in your lip products. Menthol, camphor, eucalyptus, fragrance and some flavourings may irritate already-chapped lips. If a product causes burning, stinging or tingling, stop using it instead of assuming the sensation means it is working.

When to see a dermatologist

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Most cases of dry lips can be managed with simple care, but persistent or severe cracking deserves attention. If your lips do not improve with basic care, or remain repeatedly dry, painful or cracked, speak to a dermatologist. Persistent lip problems can sometimes be associated with irritation, allergic reactions, infection or other skin conditions.

Honey can be tried as an occasional soothing ingredient, but the basics remain more important: avoid irritating the lips, keep them moisturised and use a protective ointment when they are dry or cracked.

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Beauty

5 Under-Eye Creams for Brighter-Looking Eyes and Dark Circles

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Dark circles can have several causes, including genetics, pigmentation, visible blood vessels, dehydration, allergies and the natural structure of the area beneath the eyes. This means an eye cream that works well for one person may not produce the same result for someone else.

The ingredients in an eye cream matter. Caffeine can temporarily help reduce the appearance of puffiness, while niacinamide and vitamin C are commonly used in products targeting uneven skin tone. Hyaluronic acid and ceramides can help with dryness, while retinol is often included in products aimed at fine lines and other signs of ageing.

If you are looking for an eye product available in South Africa, these five are worth considering.

CeraVe Eye Repair Cream

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CeraVe Eye Repair Cream is formulated with ceramides, hyaluronic acid and niacinamide. It is designed to hydrate the delicate skin around the eyes while supporting the skin barrier.

The formula is particularly worth considering if dryness is making the under-eye area look dull or making fine lines more noticeable.

African Extracts Rooibos Advantage Rejuvenating Eye Cream

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African Extracts offers a South African skincare option with its Rooibos Advantage Rejuvenating Eye Cream. The formula contains rooibos extract, sea fennel peptides, buckwheat seed extract and allantoin.

The product is designed for concerns including dark circles, puffiness, fine lines and dehydration, making it an option for several common under-eye concerns.

Vichy Minéral 89 Eye Fortifier

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For those who prefer a lightweight formula, Vichy’s Minéral 89 Eye Fortifier is a gel designed to hydrate and refresh the eye area. It contains hyaluronic acid and caffeine, along with Vichy’s mineralising thermal water.

Hyaluronic acid helps the skin retain moisture, while caffeine is commonly used in eye products aimed at the appearance of puffiness.

Olay Ultimate Eye Cream

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Olay Ultimate Eye Cream combines skincare ingredients with colour-correcting pigments. Its formula includes niacinamide and a peptide, while mineral pigments help reduce the appearance of dark circles immediately after application.

This makes it useful if you want an eye cream that provides both skincare benefits and a cosmetic brightening effect.

Neutrogena Retinol Boost Eye Cream

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If fine lines are your main concern, Neutrogena Retinol Boost Eye Cream offers a retinol-based option. Retinol is a form of vitamin A commonly used in anti-ageing skincare because it can support collagen production and increase skin-cell turnover.

The eye area is sensitive, so retinol products should be introduced gradually and used according to the instructions on the packaging.

Choose according to your concern

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There is no single eye cream that can remove every type of dark circle. If pigmentation is the main issue, a formula containing brightening ingredients may be more appropriate. Caffeine can be useful when puffiness is the concern, while moisturising ingredients can help when dryness makes the area look dull.

It is also worth remembering that genetics, facial structure and hollowness beneath the eyes can contribute to dark circles. In these cases, an eye cream may improve the appearance of the skin but cannot completely change the underlying cause.

Whichever product you choose, apply only a small amount around the eye area and avoid getting the product into the eyes. If you experience persistent irritation, stop using it and consider speaking to a dermatologist.

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Beauty

4 Steps to Glowing Skin, According to Experts

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Healthy-looking skin does not require a bathroom shelf full of products. A consistent routine that cleanses, moisturises, addresses specific concerns and protects against the sun can provide a stronger foundation for the complexion. The key is choosing products that suit your skin and using them consistently.

Cleanse without overdoing it

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Cleansing removes sweat, excess oil, sunscreen and makeup from the skin. A suitable cleanser should do this without leaving the face feeling tight or uncomfortable.

A simple routine is often easier to maintain than one built around multiple products. Start with a cleanser suited to your skin type, particularly if your skin is sensitive or prone to dryness.

At night, cleanse your skin thoroughly if you have worn makeup or sunscreen. In the morning, your routine can depend on how your skin feels. If it is dry or sensitive, a gentle cleanser may be preferable to a stronger formula.

Keep your skin moisturised

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Hydration is important for all skin types, including oily skin. When the skin barrier is disrupted, it can become dry, flaky, tight or more sensitive.

Moisturisers containing ingredients such as glycerin, ceramides, hyaluronic acid or squalane can help support the skin’s moisture levels. The right texture also matters. Oily or acne-prone skin may be more comfortable with a lightweight lotion or gel, while dry skin may benefit from a richer cream.

Moisturising is particularly important when using active ingredients that can cause dryness or irritation. Supporting the skin barrier can make a treatment routine easier to tolerate.

Choose a treatment for your main concern

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This is where your routine should reflect what you want to improve.

For uneven pigmentation, ingredients such as vitamin C can be considered. Salicylic acid is commonly used for acne and clogged pores, while retinoids can help with acne, uneven texture and signs of skin ageing.

Avoid introducing several strong active ingredients at the same time. Doing so can increase the risk of irritation and make it difficult to identify which product is causing a reaction. Introduce treatments gradually and give your skin time to adjust.

Most importantly, choose a treatment based on your skin concern instead of adding products simply because they are popular.

Wear sunscreen every morning

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Sun protection should be part of your morning routine, even when the weather is overcast. UV exposure contributes to premature skin ageing, pigmentation and other forms of skin damage.

Choose a broad-spectrum sunscreen with at least SPF 30 and apply it generously to exposed skin. If you are spending extended periods outdoors, reapply as directed, particularly after sweating or swimming.

For people dealing with pigmentation, a tinted sunscreen may also be worth considering. Some tinted formulas contain iron oxides, which can provide additional protection against visible light that may worsen hyperpigmentation.

Glowing skin is not about making the face look shiny. It is more useful to think about maintaining skin that is hydrated, protected and comfortable while addressing specific concerns with appropriate products.

A routine does not have to contain numerous steps to be effective. Start with the basics, introduce treatments according to your needs and give the routine enough time to work before deciding that you need something else.

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